The Glow Stack

The Glow Stack – Research Blend Kit

The Glow Stack Research Blend is a tri-peptide kit comprising GHK-Cu (50 mg), BPC-157 (10 mg), and TB-500 (10 mg) — engineered to support integrated investigations into extracellular matrix (ECM) remodelling, cytoskeletal dynamics, and antioxidant defence pathways. Designed for researchers studying collagen/elastin synthesis, cell migration, and Nrf2-mediated cytoprotection in dermal and musculoskeletal models, this stack enables controlled co-administration studies. All components are supplied as individual lyophilised solids — not pre-mixed — to ensure stability, traceability, and full regulatory compliance.

Supplied as three separate lyophilised vials (GHK-Cu 50 mg + BPC-157 10 mg + TB-500 10 mg) — never pre-formulated — for research integrity and MHRA alignment.

What is The Glow Stack Research Blend?

The Glow Stack is a RUO research kit comprising:

• GHK-Cu (CAS 40949-98-6, 50 mg): Copper-chelated tripeptide for collagen I/III, elastin, and Nrf2 pathway studies
• BPC-157 (CAS 137525-51-0, 10 mg): Stable gastric pentadecapeptide for VEGF/NO and integrin-mediated repair
• TB-500 (CAS 62568-57-4, 10 mg): Thymosin β4 fragment for actin polymerisation and cell motility

Each peptide is independently synthesised, QC-tested, and supplied with full CoA. The stack is not a cosmetic, drug, or supplement — but a research tool for combinatorial tissue resilience analysis [Pickart L, BBRC 1980; Šebečić B, JPP 1996; Bock SC, JBC 1989]. Supplied exclusively for in vitro, ex vivo, and preclinical research — not for human or veterinary use.

🔬 Note: “Glow” refers to phenotypic in vitro outcomes (e.g., enhanced ECM deposition, reduced ROS fluorescence, accelerated cell migration) — not aesthetic claims. GHK-Cu requires COSHH assessment (copper compound).

Scientific Identifiers

Usage and Reconstitution

Each peptide is reconstituted separately, per validated protocol:
✅ GHK-Cu: ultrapure H₂O or PBS (avoid chelators)
✅ BPC-157: sterile 0.9% NaCl
✅ TB-500: 0.1% acetic acid in saline or bacteriostatic water

⚠️ Critical Handling Notes:
– Do not pre-mix — solvent incompatibility (GHK-Cu degrades in acid; TB-500 aggregates in neutral pH).
– Recommended sequencing:

1. GHK-Cu (ECM priming, 24h pre-treatment)
2. BPC-157 (angiogenesis, co-administered or 2h prior)
3. TB-500 (migration phase, 0–6h post-injury) – Filter GHK-Cu through 0.22 µm PVDF (low-metal-binding); others through standard PVDF.

Post-Reconstitution Storage:
– GHK-Cu: 2–8°C (dark) ≤72 h / −80°C ≤3 mo
– BPC-157: 2–8°C ≤14 d / −80°C ≤12 mo
– TB-500: 2–8°C ≤72 h / −80°C ≤6 mo

🛒 Recommended triple reconstitution kit (H₂O + saline + acetic acid/saline) auto-added → Adjust before checkout.

The Glow Stack Research Blend: Key Investigational Pathways

This tri-peptide kit enables systems-level tissue resilience research:

• ECM Synthesis & Structural Integrity
  → GHK-Cu (collagen/elastin) + BPC-157 (fibronectin/integrin) + TB-500 (cell–ECM adhesion) in:
  • 3D dermal equivalents (tensile strength, SHG collagen imaging)
  • Tendon fibroblasts (collagen I alignment, α-SMA modulation)
  • Photoaged explants (MMP-1/TIMP-1 balance)
• Cellular Motility & Wound Closure
  → TB-500 (actin polymerisation) + BPC-157 (FAK activation) + GHK-Cu (VEGFR2 sensitisation) in:
  • Scratch assays (fibroblast/keratinocyte migration speed)
  • Diabetic murine wounds (closure rate, granulation thickness)
  • Live-cell imaging (F-actin dynamics, focal adhesion turnover)
• Oxidative Stress & Cytoprotection
  → GHK-Cu (Nrf2/HO-1) + BPC-157 (SOD) in:
  • UVB-irradiated keratinocytes (ROS: DCFDA; DNA damage: γH2AX)
  • H₂O₂-challenged tenocytes (mitochondrial health: MitoTracker)
  • Nrf2-knockout validation
• Anti-Fibrotic & Inflammatory Resolution
  → GHK-Cu (TGF-β1/Smad3 inhibition) + BPC-157 (IL-10) + TB-500 (M2 polarisation) in:
  • Keloid fibroblasts (collagen contraction, α-SMA)
  • Post-surgical adhesion models (peritoneal, tendon sheath)
  • Macrophage co-cultures (CD206⁺/iNOS⁺ ratio)

⚠️ All accessories are for laboratory use only — not medical devices. GHK-Cu requires COSHH risk assessment.

Why Order The Glow Stack from NovaVitality?

• 🔬 Triple-validated CoA’s
• 🇬🇧  UK-compliant kit: MHRA-aligned documentation, individual vial traceability, COSHH-ready
• 📚 Research-first design: Science-led — no “glow”, “radiance”, or cosmetic language
• 🛡️ RUO integrity: Meets MHRA GMP Guide, COSHH Regulations 2002, FDA 21 CFR 1271
• 💬 Stack optimisation support: Help with dose ratios (5:1:1), temporal sequencing, or 3D tissue model protocols

Legal and Safety Information

NovaVitality supplies The Glow Stack Research Blend strictly for laboratory research (RUO).

❌ This product is not approved for:
→ Human use
→ Veterinary use
→ Cosmetic, aesthetic, or supplement use

⚠️ Critical Responsibilities:
– GHK-Cu requires COSHH assessment (copper compound — mild irritant)
– Use only under institutional biosafety approval
– Do not pre-mix peptides without stability validation
– “Glow Stack” is a research-protocol nickname — not a branded product or efficacy claim

🔒 NovaVitality disclaims all liability for unauthorised use. Researchers bear full responsibility for validation and compliance.

Ready to Advance Multi-Pathway Tissue Resilience Research?

📦 [Bacteriostatic Water]
💉 [Research Syringes]
📄 [The Glow Stack Storage & Stability Datasheet]