Bacteriostatic Water COSHH Safety Data Sheet (SDS)

🖨️ NovaVitality COSHH Safety Data Sheet
Document ID: NV-SDS-BAW-001
Version: 2.1
Effective Date: 10 December 2025
Product: Bacteriostatic Water (0.9% w/v Benzyl Alcohol in 0.9% w/v Sodium Chloride) — Research Grade


🔶 SECTION 1: IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING

ItemDetails
Product NameBacteriostatic Water (0.9% Benzyl Alcohol in 0.9% NaCl) — Research Grade
UseLaboratory reagent for peptide/protein reconstitution (RUO)
SupplierNovaVitality Ltd, Cambridge, UK
Recommended UseIn vitro and ex vivo research only — not for human or veterinary therapeutic use
Emergency Contact+44 (0)20 XXXX XXXX (Mon–Fri 9am–5pm GMT)

🔶 SECTION 2: HAZARDS IDENTIFICATION

Hazard ClassClassification (CLP)H-Statements
Skin IrritationCategory 2H315: Causes skin irritation
Eye IrritationCategory 2H319: Causes serious eye irritation
Specific Target Organ Toxicity (Single Exposure)Category 3 (Respiratory tract irritation)H335: May cause respiratory irritation
Hazardous to the Aquatic EnvironmentChronic Category 3H412: Harmful to aquatic life with long-lasting effects

| Signal Word | Warning |
| Precautionary Statements (P-Statements) |
| P261: Avoid breathing dust/fume/gas/mist/vapours/spray
| P271: Use only outdoors or in well-ventilated area
| P280: Wear protective gloves/eye protection
| P302+P352: IF ON SKIN: Wash with plenty of water
| P304+P340: IF INHALED: Remove person to fresh air and keep comfortable for breathing
| P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing
| P337+P313: If eye irritation persists: Get medical advice/attention
| P501: Dispose of contents/container to approved waste disposal plant |

⚠️ Note for Researchers: Benzyl alcohol (0.9%) is not classified as hazardous under COSHH Schedule 2 (no WELs), but requires risk assessment due to irritant properties.


🔶 SECTION 3: COMPOSITION/INFORMATION ON INGREDIENTS

ComponentCAS No.Concentration (w/v)CLP Classification
Benzyl alcohol100-51-60.9%Skin Irrit. 2; Eye Irrit. 2; STOT SE 3
Sodium chloride7647-14-50.9%Not classified
Water7732-18-598.2%Not classified

No ingredients ≥1% are CMR, respiratory sensitisers, or PBT/vPvB.


🔶 SECTION 4: FIRST-AID MEASURES

ExposureFirst Aid
InhalationMove to fresh air. If breathing is difficult, give oxygen. Seek medical attention if coughing or discomfort persists.
Skin ContactRemove contaminated clothing. Wash with soap and water for 15 min. Seek medical attention if irritation persists.
Eye ContactRinse immediately with lukewarm water for ≥15 min, holding eyelids open. Remove contact lenses if present. Seek immediate medical attention.
IngestionRinse mouth. Do NOT induce vomiting. Give 1–2 glasses of water. Seek medical attention.

🚨 Never give anything by mouth to an unconscious person.


🔶 SECTION 5: FIREFIGHTING MEASURES

ParameterDetail
Extinguishing MediaWater spray, alcohol-resistant foam, dry chemical, CO₂
Specific HazardsVapours may form explosive mixtures with air. Containers may rupture when heated.
Protective EquipmentSelf-contained breathing apparatus (SCBA), full protective gear.

🔶 SECTION 6: ACCIDENTAL RELEASE MEASURES

StepAction
Personal PrecautionsVentilate area. Wear PPE (gloves, goggles, lab coat).
Environmental PrecautionsDo not discharge into drains or watercourses. Contain spill with inert absorbent (e.g., vermiculite).
Clean-up MethodsAbsorb with inert material, place in sealed chemical waste bag. Wash area with water.

🔶 SECTION 7: HANDLING AND STORAGE

RequirementGuidance
Handling• Use in well-ventilated lab (≥10 air changes/hour)
• Avoid contact with skin/eyes
• Do not pipette by mouth
• Ground containers during transfer
Storage• Store at 2–25°C, protected from light
• Keep in original amber glass vial
• Store away from strong oxidisers (e.g., H₂O₂, peracids)
Incompatible MaterialsStrong oxidising agents, isocyanates

🔶 SECTION 8: EXPOSURE CONTROLS / PERSONAL PROTECTION

ControlSpecification
Engineering ControlsFume hood recommended for >10 mL handling or open-vial work >5 min
Respiratory ProtectionNot required for routine use. If vapour >50 ppm (TLV-TWA), use N95 mask
Hand ProtectionNitrile gloves (≥0.11 mm thickness, e.g., Ansell Sol-Vex® 37-155) — breakthrough time >480 min
Eye ProtectionSafety goggles (BS EN 166 B) or face shield for splash risk
Skin ProtectionLab coat (cotton or polyester), closed-toe shoes
Hygiene MeasuresWash hands after handling. Do not eat/drink in lab.

📊 Occupational Exposure Limits (OELs):

  • Benzyl alcohol: TLV-TWA (ACGIH) = 50 ppm (228 mg/m³)
  • No UK WEL assigned — follow ACGIH TLV.

🔶 SECTION 9: PHYSICAL AND CHEMICAL PROPERTIES

PropertyValue
AppearanceClear, colourless solution
OdourFaint aromatic
pH (25°C)4.5–7.0
Density~1.00 g/mL
Boiling Point~100°C (water-dominated)
Flash Point>93°C (closed cup) — non-flammable
Solubility in WaterFully miscible
Partition Coefficient (log Kow)1.95 (benzyl alcohol)

🔶 SECTION 10: STABILITY AND REACTIVITY

ParameterDetail
StabilityStable under recommended storage.
Conditions to AvoidHigh heat (>40°C), strong oxidisers, UV light (promotes BA oxidation)
Incompatible MaterialsHydrogen peroxide, peracetic acid, isocyanates
Hazardous DecompositionCarbon monoxide, carbon dioxide, benzaldehyde (if combusted)

🔶 SECTION 11: TOXICOLOGICAL INFORMATION

EndpointFindings (Benzyl Alcohol, 0.9% dilution)
Acute Toxicity (Oral, Rat)LD₅₀ > 1,200 mg/kg (low hazard at 0.9%)
Skin Irritation (Rabbit)Mild, reversible erythema (OECD 404)
Eye Irritation (Rabbit)Moderate, reversible conjunctivitis (OECD 405)
SensitisationNot a skin sensitiser (LLNA EC3 > 20%)
Repeated Dose ToxicityNOAEL = 250 mg/kg/day (rat, 90-day) — irrelevant at research dilutions

📌 Risk Context: At 0.9% (9,000 ppm), typical peptide stock dilutions (e.g., 10 µL into 1 mL buffer) yield ≤90 ppm BAwell below TLV (50 ppm).


🔶 SECTION 12: ECOLOGICAL INFORMATION

ParameterDetail
EcotoxicityBenzyl alcohol:
Daphnia magna EC₅₀ (48h): 32 mg/L
Danio rerio LC₅₀ (96h): 45 mg/L
PersistenceReadily biodegradable (OECD 301B)
Bioaccumulationlog Kow = 1.95 → low bioaccumulation potential
Waste DisposalDispose as non-hazardous aqueous waste (EWC 20 01 27*) if <1% BA. Confirm with local authority.

🔶 SECTION 13: DISPOSAL CONSIDERATIONS

Waste StreamDisposal Method
Unused ProductEvaporate in fume hood; dispose residue as chemical waste (EWC 16 06 02*)
Contaminated MaterialsSeal in chemical waste bag — label “Benzyl alcohol-contaminated”
Empty VialsRinse ×3 with water; dispose as non-hazardous glass (EWC 15 01 07)

🇬🇧 UK Waste Code: EWC 20 01 27* — Aqueous wastes containing hazardous substances (if >1% BA); otherwise EWC 20 03 01 (non-hazardous lab waste).


🔶 SECTION 14: TRANSPORT INFORMATION

ParameterDetail
UN NumberUN3334
Proper Shipping NameENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S.
Hazard Class9 (Miscellaneous)
Packing GroupIII
Special PrecautionsProtect from sunlight. Keep container tightly closed.

🔶 SECTION 15: REGULATORY INFORMATION

RegulationStatus
UK REACHRegistered (benzyl alcohol: UK-REACH-01-0212222222-55-001)
COSHH 2002Requires risk assessment (Schedule 2: irritant)
CLP RegulationCompliant — labelled with H315, H319, H335
MHRA RUO GuidanceCompliant — supplied as research reagent, not medicinal product

🔶 SECTION 16: OTHER INFORMATION

ItemDetail
Date Prepared10 December 2025
Revision2.1 (Updated OELs, waste codes)
DisclaimerThis SDS is for research use only. NovaVitality makes no warranties regarding fitness for purpose. Users must conduct their own COSHH risk assessment.