Tirzepatide is a synthetic investigational peptide that functions as a dual GIP and GLP-1 receptor agonist. It is the active ingredient in Mounjaro®, an FDA-approved medication for type 2 diabetes management.
In research settings, Tirzepatide has attracted considerable interest for its ability to regulate insulin response, control blood glucose levels, and promote substantial weight reduction through appetite suppression and improved metabolic function.
How Does It Work?
Tirzepatide mimics two incretin hormones:
- GIP (glucose-dependent insulinotropic polypeptide): Enhances insulin secretion in response to glucose.
- GLP-1 (glucagon-like peptide-1): Slows gastric emptying, reduces glucagon secretion, and regulates appetite.
By activating both pathways, Tirzepatide improves glucose metabolism, enhances satiety signals, and reduces caloric intake. This dual action distinguishes it from traditional GLP-1 agonists, making it particularly valuable in obesity and metabolic research models.
Key Benefits Reported in Research
- Improves insulin sensitivity and glycemic control
- Reduces appetite and increases satiety
- Supports meaningful weight reduction in clinical trials
- Lowers HbA1c levels in diabetes studies
- Shows potential to improve multiple markers of metabolic dysfunction
Research Overview
Clinical investigations suggest that Tirzepatide can outperform single incretin agonists by combining GIP and GLP-1 activity. Results have shown significant improvements in HbA1c and body weight reduction, positioning Tirzepatide as one of the most promising compounds in metabolic and obesity research.
Usage and Application
Tirzepatide is supplied strictly for in vitro research and laboratory use only. It is not intended for medical, human, or veterinary use. Research applications include:
- Insulin and glucose metabolism pathways
- Appetite and satiety regulation
- Obesity intervention models
- Comprehensive metabolic health studies
Storage and Handling
- Store lyophilized Tirzepatide in a cool, dry environment.
- After reconstitution with bacteriostatic water or another suitable solvent, refrigerate and use within the recommended stability window.
Disclaimer
Tirzepatide is sold exclusively for laboratory research purposes. It is not intended for human consumption or veterinary use.
